Miki Fujimura Selected Research

Ischemia

1/2022	Moyamoya Disease-Standards and Advances in Revascularization Procedure and Peri-operative Management.
1/2020	The hemodynamic complexities underlying transient ischemic attacks in early-stage Moyamoya disease: an exploratory CFD study.
1/2018	Stress-induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells.
7/2015	Consistent delayed unilateral neuronal death after modified transient focal cerebral ischemia in mice that mimics neuronal injury after transient global cerebral ischemia.
1/2015	Enhanced post-ischemic angiogenesis in mice lacking RNF213; a susceptibility gene for moyamoya disease.
8/2014	SMTP-7, a new thrombolytic agent, decreases hemorrhagic transformation after transient middle cerebral artery occlusion under warfarin anticoagulation in mice.
1/2012	Lessons learned from moyamoya disease: outcome of direct/indirect revascularization surgery for 150 affected hemispheres.
5/2003	Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia.
1/2002	Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.
1/2002	Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke.

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Miki Fujimura Research Topics

Disease

24	Moyamoya Disease (Moya-Moya Disease) 08/2022 - 11/2009
16	Aneurysm (Aneurysms) 04/2020 - 01/2011
14	Hemorrhage 01/2021 - 04/2007
10	Ischemia 01/2022 - 01/2002
10	Brain Ischemia (Cerebral Ischemia) 01/2020 - 01/2002
8	Stroke (Strokes) 01/2022 - 01/2002
8	Cysts 06/2020 - 02/2008
6	Edema (Dropsy) 04/2020 - 02/2009
6	Infarction (Infarctions) 01/2015 - 07/2008
5	Neoplasms (Cancer) 06/2020 - 11/2007
5	Hydrocephalus (Hydrocephaly) 09/2018 - 03/2009
4	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 09/2018 - 03/2012
4	Reperfusion Injury 01/2018 - 05/2003
4	Cerebral Infarction 01/2017 - 10/2011
3	Inflammation (Inflammations) 01/2022 - 11/2018
3	Disease Progression 01/2022 - 08/2015
3	Intracranial Aneurysm (Cerebral Aneurysm) 04/2020 - 05/2018
3	Cerebral Hemorrhage 02/2019 - 08/2014
3	Rupture 01/2019 - 12/2015
3	Pathologic Constriction (Stenosis) 09/2017 - 01/2014
3	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2017 - 01/2011
3	Vascular Remodeling 01/2016 - 12/2014
3	Hyperplasia 10/2015 - 03/2014
3	Transient Ischemic Attack 09/2014 - 05/2003
3	Brain Injuries (Brain Injury) 10/2011 - 01/2005
3	Atherosclerosis 10/2011 - 04/2010
2	Spinal Cord Injuries (Spinal Cord Injury) 01/2022 - 01/2021
2	Meningioma (Meningiomas) 01/2022 - 01/2016
2	Ischemic Stroke 01/2022 - 01/2022
2	COVID-19 12/2021 - 01/2021
2	Hypotension (Low Blood Pressure) 10/2021 - 09/2017
2	Embolic Stroke 01/2021 - 10/2011
2	Arteriovenous Malformations (Arteriovenous Malformation) 01/2021 - 04/2013
2	False Aneurysm (Pseudoaneurysm) 04/2020 - 05/2019
2	Hemorrhagic Stroke 01/2020 - 01/2019
2	Hematoma 12/2019 - 11/2007
2	Craniopharyngioma (Craniopharyngiomas) 05/2019 - 09/2018
2	Aortic Dissection 01/2018 - 07/2010
2	Meningitis 09/2016 - 12/2015
2	Hyponatremia 12/2015 - 04/2014
2	Thinness 10/2015 - 03/2014

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 08/2022 - 01/2004
5	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2014 - 11/2009
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2014
4	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2021 - 10/2017
3	CytokinesIBA 01/2022 - 01/2016
3	Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)IBA 02/2019 - 07/2010
3	Minocycline (Cyclops)FDA LinkGeneric 11/2018 - 02/2014
3	TitaniumIBA 11/2018 - 08/2015
3	Free Radical ScavengersIBA 11/2018 - 07/2015
3	Caspase 3 (Caspase-3)IBA 07/2015 - 01/2002
3	Superoxides (Superoxide)IBA 10/2011 - 01/2002
2	Protons (Proton)IBA 01/2021 - 04/2013
2	Warfarin (Coumadin)FDA LinkGeneric 01/2021 - 08/2014
2	EnbucrilateIBA 04/2020 - 01/2015
2	Contrast MediaIBA 01/2019 - 10/2018
2	Biological ProductsIBA 01/2019 - 11/2008
2	Indicators and Reagents (Reagents)IBA 01/2019 - 10/2018
2	Pharmaceutical PreparationsIBA 11/2018 - 01/2017
2	Anticonvulsants (Antiepileptic Drugs)IBA 11/2018 - 08/2018
2	Oxygen (Dioxygen)IBA 01/2018 - 01/2002
2	Messenger RNA (mRNA)IBA 09/2017 - 01/2016
2	Acetazolamide (Diamox)FDA LinkGeneric 01/2017 - 05/2016
2	Rubber (Elastica)IBA 10/2015 - 03/2014
2	GadoliniumIBA 08/2015 - 01/2015
2	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 07/2015 - 05/2003
2	SMTP 7IBA 08/2014 - 10/2011
2	Fibrinolytic Agents (Antithrombotic Agents)IBA 08/2014 - 10/2011
2	Tissue Plasminogen Activator (Alteplase)FDA Link 08/2014 - 10/2011
2	LipidsIBA 11/2013 - 01/2004
2	Neuroprotective AgentsIBA 10/2011 - 01/2005
2	Matrix Metalloproteinases (MMPs)IBA 07/2010 - 11/2009
2	EnzymesIBA 11/2009 - 01/2005
2	CaspasesIBA 04/2007 - 01/2002
2	CopperIBA 01/2005 - 01/2002
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2005 - 01/2004
2	Superoxide DismutaseIBA 01/2005 - 01/2002
2	ZincIBA 01/2005 - 01/2002
2	Cytochromes c (Cytochrome c)IBA 01/2002 - 01/2002

Therapy/Procedure

12	Therapeutics 04/2022 - 03/2003
8	Catheters 01/2022 - 11/2012
8	Cerebral Revascularization 01/2022 - 07/2008
8	Craniotomy 04/2020 - 05/2003
7	Radiotherapy 06/2020 - 01/2004
7	Surgical Instruments (Clip) 04/2019 - 01/2009
6	Ligation 04/2020 - 03/2014
4	Operative Surgical Procedures 01/2022 - 01/2019
4	Endoscopes 01/2020 - 03/2009
4	Lasers (Laser) 09/2018 - 03/2012
4	Ventriculostomy 01/2017 - 03/2009
3	Thrombectomy 01/2022 - 01/2021
3	Sutures (Suture) 07/2015 - 03/2012
3	Cesarean Section (Caesarean Section) 01/2014 - 12/2012
2	Injections 04/2022 - 01/2021
2	Precision Medicine 01/2022 - 01/2022
2	General Anesthesia 10/2021 - 01/2021
2	Cranial Irradiation 06/2021 - 05/2019
2	Decompression 01/2020 - 01/2009
2	Off-Label Use 01/2017 - 05/2016
2	Perioperative Period 01/2015 - 08/2014